CASE STUDY

Yale New Haven Hospital virtually eliminates sample rejections from hemolysis

Yale New Haven Hospital

New Haven, Connecticut · 1,541 beds · View Website

Collaborators:
Joe El-Khoury, PhD, DABCC, FAACC
Christopher Koch, PhD

Koch et al. AACC (2020)

 
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“Vibration metrics from VitalQC are useful indicators of g-forces experienced by blood tubes and correlate with hemolysis.”


Dr. Joe El-Khoury,
Yale New Haven Hospital

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Challenge

Blood samples from the Neonatal Intensive Care Unit (NICU) are prone to hemolysis, either representing the patient’s health, or due to collection and transport which can reduce specimen quality. Yale New Haven Hospital was looking to test how interventions in sample transport could improve specimen quality from high-rejection-rate patient-care areas.

 
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Solution

With VitalQC, Drs. Joe El-Khoury and Christopher Koch could measure the effect of placing samples in foam padding inside the Pneumatic Tube System (PTS) carriers. The PTS transports samples from the NICU to the lab for analysis, but can introduce considerable vibration that can break down red blood cells. VitalQC measured how much the padding reduced overall vibration, which was expected to reduce hemolysis. Blood sample rejection was compared for samples sent with and without foam padding.

 
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Results

Total vibration measured with VitalQC was 30% lower in padded carriers. The reduction in vibration led to the virtual elimination of sample rejection due to hemolysis: from 11% (17/150 samples) without padding to 0% (0/56) with foam padding.

With data from VitalQC, Yale New Haven gained the insights to support a new SOP to reduce sample rejections.

 
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About Yale New Haven Hospital

Yale New Haven Hospital consistently ranks among the best hospitals in the United States.

Serving as the primary teaching hospital for Yale School of Medicine, YNHH is focused on educating the brightest young minds for medical leadership in clinical practice, teaching and research. YNHH has demonstrated its commitment to advancing medicine by developing, testing and introducing leading-edge technologies and treatments to the global medical community.

VitalQC revealed that padding
reduced vibration by

30%

This discovery reduced PTS-induced
hemolysis from 11% to

0%

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